标签归档 上海夜网论坛

　　Pfizer CEO Abel Le data map

　　What kind of treatment plan will the CEO of "the first pharmaceutical factory in the universe" accept after his nucleic acid test is positive?

　　On August 15th, local time, official website of Pfizer (NYSE：PFE) issued a statement saying that CEO Albert Bourla tested positive for COVID-19. In a statement, Albright said that she had been vaccinated with four doses of Pfizer/Bionta COVID-19 vaccine, and she felt good but had mild symptoms. She was being quarantined and following public health precautions. In terms of treatment, I have started taking Paxlovid, the company’s oral medicine for COVID-19.

　　Abel said that he believes that he will recover soon.

　　Who’s Abel?

　　On October 1, 2018, Pfizer announced that the board of directors of the company unanimously elected 56-year-old Pfizer COO Abel as CEO of Pfizer, which took effect on January 1, 2019.

　　According to the official information released by Pfizer China at that time, before becoming COO on January 1, 2018, Abreu led Pfizer’s innovative medical business and established innovative medical emerging market areas. Prior to being appointed as the head of Pfizer’s innovative medical business, Ai Bole became the president of the Vaccine, Oncology and Health Drugs Business Group in January 2014. Under his leadership, the tumor business has tripled in four years, the vaccine business has increased by 50%, and the health medicine business has significantly improved its profitability.

　　In addition, Arbelot also led several key transactions to promote Pfizer’s investment portfolio in the fields of cancer, inflammation and immunity, vaccines and rare diseases, and to create a strong and leading cancer business in the franchise field of breast cancer and prostate cancer through priority investment.

　　The history of Pfizer can be traced back to 1849, and it is headquartered in new york, USA. During its development, the forms of acquisition, merger and sale have gradually developed. As the world’s top pharmaceutical company, Pfizer was once called "the first pharmaceutical company in the universe" in the pharmaceutical industry. Under the leadership of Albrecht, Pfizer has made many changes, such as divesting generic drug business in 2020, which was called "the first year of transformation" by Pfizer in 2021, and the company is transforming into a scientific-based, innovative and patient-oriented biopharmaceutical company.

　　It was also during the period when Albrecht served as CEO that the world experienced the test of COVID-19 epidemic. Pfizer obtained the preventive mRNA COVID-19 vaccine through cooperation with BioNtech, and promoted the use of Paxlovid, a small molecular oral drug in COVID-19, in many markets. These two products also led to the soaring performance of Pfizer. According to the revenue data in 2021, Pfizer ranks second in the world, second only to Johnson & Johnson.

　　In the second quarter, COVID-19’s vaccine and oral medicine contributed 12.6 billion US dollars in revenue.

　　In the statement, Aibole mentioned that he had been vaccinated with COVID-19 vaccine and was taking oral medicine, which was also the driving force for Pfizer’s strong performance.

　　On July 28th, local time, Pfizer released its financial report for the second quarter of 2022, showing that its revenue in the second quarter was US$ 27.7 billion, a year-on-year increase of 47%. In terms of net profit, the revenue in the second quarter was 9.91 billion US dollars, a year-on-year increase of 78%. "In the second quarter, we achieved the largest quarterly sales in history," Pfizer quoted Abel as saying in a press release.

　　Some data of Pfizer’s second quarterly report

　　Behind the growth of revenue in the second quarter, it mainly benefited from the contribution of Paxlovid, a new oral drug, and Comirnaty, an mRNA COVID-19 vaccine. Specifically, COVID-19’s sales of oral drugs were $8.1 billion, and COVID-19’s sales of vaccines were $8.8 billion. Together, they contributed $12.6 billion in revenue, accounting for about 45% of the total revenue in the second quarter.

　　At the end of 2021, the US Food and Drug Administration (FDA) urgently approved Pfizer’s COVID-19 oral drug Paxlovid, which was also the first approved oral COVID-19 drug in the United States. According to the second quarterly report, in the second quarter, the drug was sold in the United States for $4.5 billion, accounting for about 55% of the market sales in the current quarter. According to Pfizer’s first quarterly report this year, the drug contributed $1.47 billion in revenue in the first quarter, with sales in the US market accounting for 69%. Pfizer’s annual sales guideline for the drug remained at $22 billion.

　　Comirnaty is an mRNA COVID-19 vaccine that Pfizer cooperated with Baiou Entai Company. It was first approved for trial in the United States and other countries and regions at the end of 2020. The second quarter financial report showed that the revenue of the vaccine in the United States was $1.1 billion, down by 47%, while it increased by 43% in other international regions. By July 20th, more than 3.6 billion doses of vaccine had been distributed to 180 countries and regions.

　　Pfizer expects the annual revenue range to be $98 billion to $102 billion, which is consistent with previous forecasts.

On the eve of the National Day (September 30), a new sub-brand – Buick Avenir was officially launched. According to SAIC GM’s strategic intention, the new brand will be specially built based on Buick’s high-end models, providing consumers with high-end and personalized car needs and exclusive service experience.

Avenir concept car built by Buick’s global team

In fact, it is not surprising that SAIC GM has taken this step. The launch of Buick Avenir is a more substantial step for Buick to advance to the high-end field in recent years. In fact, Buick has launched high-end models such as Rongyu and other high-end models before. At the Boao Forum for Asia in 2008, the organizers chose Buick Boulevard as the "only designated VIP car". Buick has also been leveraging cultural and artistic platforms to enhance brand perception, and a series of brand promotion and sponsorship activities have indeed effectively solidified the foundation of Buick’s brand’s continuous improvement.

The practice of providing high-end models through the release of sub-brands on the basis of existing models is actually not unique to Buick. For example, the version of the model, such as the Vignale version, and then looking back, you can also find the Ford Ghia brand. If we expand the definition of sub-brands from high-end to sports, we will also include such things as the Polaris series, series, etc. The case has proved that the introduction of sub-brands can quickly increase brand influence and model awareness.

However, all of this is also conditional.

First of all,The premise of enhancing brand influence through the launch of high-end sub-brands is that the brand itself requires basic brand power.

When we turn back the clock of history, we always find the intersection of Buick and the upper class. General Zhang Xueliang’s special car was a Buick, and President Roosevelt’s gift to Qingling was a black Buick, Premier Zhou’s exclusive car or a Buick.

As one of the early brands to enter the Chinese market, the Buick brand has gained a certain reputation in the luxury car market in the early years by virtue of the advantages of imported cars and the early domestic Buick Century and other models. Subsequently, with the launch of a series of family sedans such as Buick, the Buick brand has also completed a wider coverage of the brand, realizing the transformation of Wang Xie in the old days and flying into the homes of ordinary people. After more than ten years of hard work, the Buick brand has become one of the most influential mainstream brands in the Chinese auto market. Many consumers regard Buick as a mid-to-high-end brand, which is the basis for the brand to continue to improve.

In recent years, Buick has improved its market share and brand span through the rapid update of models and the continuous enrichment of its product lineup. At present, the Buick brand has completed the layout of three major car series: high-end comfortable models, high-end coupes, and high-end SUVs, and has opened the product layout of "Buick Blue" new energy vehicles, which constitutes the first premise for the release of the Avenir sub-brand.

Secondly,Brands must have sufficient product strength and sales to support the development of high-end sub-brands.

Compared with the parent brand, the sub-brand is still a niche after all, not to mention that the sub-brand of Buick Avenir still relies on the development idea of the parent brand’s existing models. Therefore, this puts forward higher requirements for the sales and product strength of the parent brand.

Let’s take a look at Buick’s recent market performance.

According to relevant data, in the first three quarters of this year, the brand completed sales of 870,104 vehicles, an increase of 26.89% year-on-year. In the most recent August and September, the SAIC-GM Buick brand completed monthly sales of more than 100,000 vehicles for two consecutive months. In terms of sub-models, 26,448 vehicles were sold in September, 8,999 vehicles were sold, 8,000 vehicles were sold, 36,386 vehicles were sold, 17,992 vehicles were sold, and 56,333 vehicles were sold in the first three quarters. Among them, Envision’s sales in September increased by 82.2% year-on-year, setting a record high in sales for the month. The cumulative sales in January-September reached 18,028 vehicles, successfully occupying the first position in the joint venture SUV market.

The SUV market is currently the fastest growing market in the domestic market. According to the statistics of the China Association of Automobile Manufacturers, the average growth rate of the SUV market is more than 50%. In this segment, the Buick Envision is in the first camp of the sales rankings and is one of the few joint venture SUVs in the top ten SUV sales rankings.

From the product point of view, the success of the Buick Envision lies in cleverly grasping the connection point between the mid-range SUV and the compact SUV, which is the pain point of the joint venture SUV market. Take the mainstream compact SUV as an example. Under the standard styling ratio, the compact SUV, especially the joint venture brand’s compact SUV, often has the disadvantage of small size and space. The mid-range SUV above this has caused young consumers to have some concerns because of its excessive size. The appearance of the Envision just solves this contradiction.

In fact, I think the Envision’s positioning is still very forward-looking. This level of SUV is a huge market that is rapidly heating up, and in addition to the Envision, there will be more models to join the competition in the future. For example, the Kodiaq just unveiled at the Paris International Motor Show this year, and the new generation of long-wheelbase Tiguan that is about to debut, the new generation of fully enlarged size, and so on.

In the large MPV market, no one can shake the position of the Buick GL8. The success of the Buick GL8 lies in providing a very rich selection of product camps in the MPV market to adapt to diverse consumer needs. The upcoming new generation GL8 also realizes comprehensive coverage from the business MPV market to the high-end private MPV market. Such volume is rare in the current MPV market. For example, the smaller size has always been a household attribute that is larger than the business attribute. In addition, from the perspective of the product, in the MPV market, the Buick GL8’s driving texture will better fit the market’s perception of MPV, including the smoothness of the power, the comfort of the chassis, and so on.

From a design perspective, the success of the new LaCrosse lies in the deepening of American design. The design of the new generation of LaCrosse brings the design of traditional American luxury cars into the design language. The interior pays attention to a comprehensive sense of wrapping and the use of warm colors. In the exterior design, sculptural aesthetics are integrated into the design to stretch the lines of the whole car. The posture of the new LaCrosse is highly consistent with the positioning of its mainstream consumer population, which is the key to its success.

In the family car market, New Yinglang has been a dark horse since its launch last year. The key to success in this market segment is actually two points. To create a well-balanced sedan under a good brand, New Yinglang has indeed achieved this. On the other hand, Valeant is on this basis to emphasize the quality of the vehicle itself and better cater to the overall positioning of the Buick brand.

In terms of the application of new technologies, the Buick brand has always been a pioneer in in-vehicle technology upgrades. For example, the first generation of the OnStar system pioneered in-vehicle intelligence. At present, Buick is also a loyal fan of green intelligent technology. The latest generation of in-vehicle intelligent interconnection system integrates 4GLTE, Apple CarPlay, Baidu CarLife and other interconnection functions. And this series of Internet technologies has been rapidly popularized in Buick’s models, providing users with a car experience in the Internet + era. Therefore, whether it is from the perspective of the overall sales volume of the Buick brand, the positioning of sub-models and the application of new technologies, the Buick brand has the scale to support a high-end sub-brand.

And thirdly,The improvement of service level is a necessary condition to support the development of high-end sub-brands.

If the product itself is regarded as the hardware facilities that support the development of high-end sub-brands, then the service is the software facilities behind it. Especially for high-end sub-brands like Buick Avenir that rely on the development of the parent brand, the premise of its birth is that the service of the parent brand meets its high-end needs.

In the field of after-sales services, Buick has indeed always paid attention to the shaping of brand perception. In 2002, Buick created China’s first after-sales services brand "Buick Care", which brought automotive after-sales services from traditional passive services to the era of active care, emphasizing the initiative of after-sales services. In May this year, Buick Care released a new brand identity and launched a series of innovative service projects. To comprehensively improve the service experience and provide users with a more contemporary service concept, the upgrade of "Buick Care" is also an important step to enhance the value of the Buick brand. With the launch of the Avenir sub-brand, it is expected that Buick Care will also launch exclusive services for the Avenir sub-brand.

It is not difficult to find that the release of the Buick Avenir sub-brand is accompanied by the overall improvement of the Buick brand’s brand influence, product strength and service capabilities, which is also an inevitable development of the brand. In turn, the release of the Avenir sub-brand will further meet the needs of the Buick brand in the high-end consumer market after the brand power is enhanced, which complement each other.

So, to answer the question raised by the title of this article, the answer is yes. For Buick, now is indeed the time to break through. Of course, shaping a new sub-brand also requires the baptism of the market and time, we will wait and see.

　　In the information age, people are increasingly inseparable from computers, which are needed for work, life, entertainment and so on. Desktop computers are bulky and not easy to carry, and they may also be needed for business trips and travel, so it is very important to buy a notebook computer. Walking around the computer city, you can see nearly a thousand computers, each of which claims to have various advantages, which makes consumers very headache and doesn’t know which laptop to choose. Xiaobian made a notebook computer purchase guide, you can learn about it.

　　The most comprehensive laptop shopping strategy to share.

　　1. Multipurpose: If you buy a laptop to watch videos, play games, handle work, etc., and you don’t concentrate on it, it’s best to touch everything, then a low-end 15-inch computer or a 13-inch door-level model is the best choice, and the price is between 2,500 and 5,000 yuan.

　　2. Business: If you are a business person, you can buy a notebook computer to process documents and various forms, then you can buy a business computer. They are durable, feel good, light and easy to carry, and have a high screen pixel. The price is 4,000-7,000 yuan.

　　3. Games: If you are a young man and buy a laptop mainly to play high-end games, then the performance of the computer is required to be very good, regardless of the processor, graphics card and screen resolution. The price of this kind of products is relatively high, generally starting from 7000 yuan.

　　4. Media workers: People engaged in media work need creativity, and they often have to open various softwares to edit videos and photos. Therefore, computer processors are required to be relatively powerful, and independent graphics cards can support the operation of various large-scale image processing software. The price of such computers starts from 4,000 yuan.

　　5. Brand is very important. At present, many brands produce notebook computers, so choosing a well-known brand will definitely be better than an unknown brand, because the after-sales service of well-known brands is relatively perfect, and problems with notebook computers can be properly handled. For example, Sony, Acer, Apple, Hewlett-Packard, Samsung, Lenovo, Asus and other brands are relatively well-known brands in notebook computers at present.

　　6. Type. At present, there are many kinds of notebook computers on the market, including tablet/notebook in one, which can meet people’s daily needs. There are also multi-mode laptops, which can also bring different experiences to people.

　　After reading the notebook computer selection guide, do you know something about purchasing a notebook computer? In fact, it is not difficult to choose the right notebook for yourself. The key is to start from your own standpoint and take personal needs and economic strength as the main factors in purchasing. When buying a laptop, you should never follow the shopping guide and blindly sell it, so you can’t buy your own laptop.

　　The three major stock indexes of A-shares fluctuated slightly in the morning, and the decline was slightly enlarged in the afternoon. At the close, the Shanghai Composite Index reported 3,043 points, down 0.40%, the Shenzhen Stock Exchange Index reported 9,604 points, down 0.27%, and the Growth Enterprise Market Index reported 1,895 points, down 0.579%. The turnover of the two cities broke through another trillion yuan.

　　In terms of sectors: Internet, media and entertainment, software services, automobiles, Sora concepts are relatively better, while non-ferrous metals, electricity, components, petroleum and other sectors closed up;

　　On the decline list, insurance, real estate, agriculture, forestry, animal husbandry and fishery, brokerage and building materials were among the top losers.

　　Capital flow: As of the closing of A-shares, statistics show that northbound capital has bought a total of 1.567 billion yuan, of which Shanghai Stock Connect bought 649 million yuan and Shenzhen Stock Connect bought 918 million yuan. The turnover of northbound funds was 135.776 billion yuan, accounting for 12.87% of the total turnover of A shares, and the trading activity decreased by 13.03%, of which Shanghai Stock Connect bought 31.544 billion yuan and sold 30.895 billion yuan, while Shenzhen Stock Connect bought 37.128 billion yuan and sold 36.210 billion yuan. Northbound funds kept net purchases for four consecutive days, with net purchases of 6.001 billion yuan, 10.260 billion yuan, 4.244 billion yuan and 1.567 billion yuan respectively, with a total net purchase of 22.072 billion yuan.

　　Regarding the trend of A-shares, Guosheng Securities believes that as the "combination boxing" of stabilizing the capital market continues to land, economic data will be released in March or will exceed expectations, which will significantly boost risk appetite and investor confidence and drive the market risk appetite to rebound. The rebound is not over yet. If there is a shock adjustment in the short term or a benign adjustment on the way up. In the medium term, with the intensive introduction of steady growth policies, the process of economic recovery is expected to accelerate, and incremental funds may return to the rebound stage, and the amount of attention can be simultaneously enlarged. At the same time, after the registration system is fully implemented, its survival of the fittest mechanism will help the market style tend to be "blue-chip", and the intermediate market of the Shanghai Composite Index will not be absent but will only deepen. At present, it is suggested to maintain a balanced allocation with value slightly greater than growth.

　　Huajin Securities pointed out that blue-chip stocks are dominant and balanced. (1) Style: In the second quarter, it shifted from micro-stocks to super-large stocks and small and medium-sized stocks; The simultaneous strengthening of dividends and technology may continue in the short term, and the short-term growth and value are balanced; In the medium term, it may be biased towards technology and growth. (2) Based on the macro-environment orientation, profit and prosperity expectation orientation, PB-ROE orientation and PEG orientation, it is suggested to pay attention in the second quarter: First, TMT, Electric Power, Machinery, Automobile, etc. with upward profit and prosperity and high valuation cost performance; Second, buildings, banks, transportation and consumption that benefit from policy and economic restoration.